Median mean SSIM across all 1,341 pairs with data: 0.322. The typical confusables.txt entry is not visually confusable at all.
This was especially vexing to physician and bacteriologist Robert Koch, who, in seeking to culture his bacteria, “bent all his power to attain the desired result by a simple and consistently successful method,” wrote bacteriologist and historian William Bulloch in his 1938 book, The History of Bacteriology. “He attempted to obtain a good medium which was at once sterile, transparent, and solid” and got some results with gelatine.6 But gelatine is easily digested by many microbes and melts at precisely the temperatures at which the disease-causing microbes Koch wanted to study grow best.
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The first symptoms include a fever, muscle aches and pains and generally feeling unwell.